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Clinical application of a real-time polymerase chain reaction test for CYP2C19 genotyping based on genotype distribution in a healthy Korean population.

Laboratory medicine - 7 Mar 2024

Park Kuenyoul, Yoo Soo Jin

Abstract excerpt

OBJECTIVE: With the recent reports of additional alleles of the CYP2C19 gene with decreased or no function, the clinical utility of real-time polymerase chain reaction (PCR)-based testing that detects only a small number of variant targets needs to be evaluated. METHOD: We retrospectively reviewed 7-year data for real-time PCR test records from a single hospital and analyzed CYP2C19 genotypes from publicly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37543868
DOI: 10.1093/labmed/lmad070

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