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Article

The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily.

Molecular and cellular biology - 1 Feb 1999

Nawaz Z, Lonard D M, Smith C L, Lev-Lehman E, Tsai S Y, Tsai M J, O'Malley B W

Abstract excerpt

In this study, we found that the E6-associated protein (E6-AP/UBE3A) directly interacts with and coactivates the transcriptional activity of the human progesterone receptor (PR) in a hormone-dependent manner. E6-AP also coactivates the hormone-dependent transcriptional activities of the other members of the nuclear hormone receptor superfamily. Previously, it was shown that E6-AP serves the role of a...

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Identifiers

PMID: 9891052
DOI: 10.1128/MCB.19.2.1182
PMCID: PMC116047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily.PMID 9891052Read ↗

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UBE3A "mutations" in two unrelated and phenotypically different Angelman syndrome patients.Semantic proximity Read ↗

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