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Article

Comparative sequences of the Wolbachia genomes of drug-sensitive and resistant isolates of Dirofilaria immitis.

Veterinary parasitology - 1 Oct 2020

Shin Pei-Tsz, Baptista Rodrigo de Paula, O'Neill Connor M, Wallis Connor, Reaves Barbara J, Wolstenholme Adrian J

Abstract excerpt

The recent identification of isolates of D. immitis with confirmed resistance to the macrocyclic lactone preventatives presents an opportunity for comparative genomic studies using these isolates, and examining the genetic diversity within and between them. We studied the genomes of Wolbachia endosymbionts of five isolates of D. immitis maintained at the University of Georgia. Missouri and Georgia-2 are...

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Identifiers

PMID: 32937243
DOI: 10.1016/j.vetpar.2020.109225
PMCID: PMC7584739

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