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Article

Predicted leukocyte telomere length and risk of myeloid neoplasms.

Human molecular genetics - 4 Oct 2023

Sullivan Shannon M, Cole Ben, Lane John, Meredith John J, Langer Erica, Hooten Anthony J, Roesler Michelle, McGraw Kathy L, Pankratz Nathan, Poynter Jenny N

Abstract excerpt

Maintenance of telomere length has long been established to play a role in the biology of cancer and several studies suggest that it may be especially important in myeloid malignancies. To overcome potential bias in confounding and reverse causation of observational studies, we use both a polygenic risk score (PRS) and inverse-variance weighted (IVW) Mendelian randomization (MR) analyses to estimate the...

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Share to Leukocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37531260
DOI: 10.1093/hmg/ddad126
PMCID: PMC10549790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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