Article
Causality between Telomere Length and the Risk of Hematologic Malignancies: A Bidirectional Mendelian Randomization Study.
Cancer research communications - 1 Oct 2024
Jiang Guoyun, Cao LingXiao, Wang Yunshan, Li Li, Wang Zie, Zhao Hui, Qiu Yang, Feng Bin
Abstract excerpt
Growing evidence indicates a relationship between telomere length (TL) and the stage, prognosis, and treatment responsiveness of hematopoietic malignancies. However, the relationship between TL and the risk of hematologic malignancies remains unclear, considering the vulnerability of observational studies to potential confounding and reverse causation. A two-sample bidirectional Mendelian randomization (MR)...
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