Article
Hairy cell leukaemia with unusual BRAF mutations.
Journal of cellular and molecular medicine - 1 Sept 2023
Maitre Elsa, Macro Margaret, Troussard Xavier
Abstract excerpt
Hairy cell leukaemia (HCL) diagnosis is based on the morphologic detection of circulating abnormal hairy cells in the peripheral blood and/or bone marrow, an HCL immunological score of 3 or 4 based on the expression of the CD11c, CD25, CD103 and CD123 and also the presence of a BRAF V600E activating mutation in the B-raf proto-oncogene (BRAF gene) (7q34). When using new generation sequencing of 21 targeted genes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
