Article
Hairy cell leukaemia-variant: Disease features and treatment.
Best practice & research. Clinical haematology - 1 Dec 2015
Matutes Estella, Martínez-Trillos Alejandra, Campo Elias
Abstract excerpt
Hairy cell leukaemia-variant (HCL-V) is a rare B-cell malignancy that affects elderly males and manifests with splenomegaly, lymphocytosis and cytopenias without monocytopenia. The neoplastic cells have morphological features of prolymphocytes and hairy cells. The immunophenotype is that of a clonal B-cell CD11c and CD103 positive but, unlike classical HCL, CD25, CD123 and CD200 negative. The spleen histology is...
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