Article
Associations of classical HLA alleles with depression and anxiety.
HLA - 1 Jan 2024
Cheng Bolun, Yang Jian, Cheng Shiqiang, Pan Chuyu, Liu Li, Meng Peilin, Yang Xuena, Wei Wenming, Liu Huan, Jia Yumeng, Wen Yan, Zhang Feng
Abstract excerpt
Immune dysregulation has been widely observed in patients with psychiatric disorders. This study aims to examine the association between HLA alleles and depression and anxiety. Using data from the UK Biobank, we performed regression analyses to assess the association of 359 HLA alleles with depression and anxiety, as determined by Patient Health Questionnaire (PHQ) score (n = 120,033), self-reported depression...
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