Article
Vitamin D and the Risks of Depression and Anxiety: An Observational Analysis and Genome-Wide Environment Interaction Study.
Nutrients - 24 Sept 2021
Zhang Zhen, Yang Xuena, Jia Yumeng, Wen Yan, Cheng Shiqiang, Meng Peilin, Li Chun'e, Zhang Huijie, Pan Chuyu, Zhang Jingxi, Chen Yujing, Zhang Feng
Abstract excerpt
Previous studies have suggested that vitamin D (VD) was associated with psychiatric diseases, but efforts to elucidate the functional relevance of VD with depression and anxiety from genetic perspective have been limited. Based on the UK Biobank cohort, we first calculated polygenic risk score (PRS) for VD from genome-wide association study (GWAS) data of VD. Linear and logistic regression analysis were conducted...
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