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Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank

25 Mar 2021

Abstract excerpt

Epidemiological studies report increased comorbidity between depression and autoimmune diseases. The role of shared genetic influences in the observed comorbidity is unclear. We investigated the evidence for pleiotropy between these traits in the UK Biobank (UKB). We defined autoimmune and depression cases using hospital episode statistics, self-reported conditions and medications, and mental health...

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PMID: 34278373
DOI: 10.1016/j.bpsgos.2021.03.002

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