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Regulatory Variants on the Leukocyte Immunoglobulin-Like Receptor Gene Cluster are Associated with Crohn's Disease and Interact with Regulatory Variants for TAP2.

Journal of Crohn's & colitis - 27 Jan 2024

Kim Kwangwoo, Oh Shin Ju, Lee Junho, Kwon Ayeong, Yu Chae-Yeon, Kim Sangsoo, Choi Chang Hwan, Kang Sang-Bum, Kim Tae Oh, Park Dong Il, Lee Chang Kyun

Abstract excerpt

BACKGROUND AND AIMS: Crohn's disease [CD] has a complex polygenic aetiology with high heritability. There is ongoing effort to identify novel variants associated with susceptibility to CD through a genome-wide association study [GWAS] in large Korean populations. METHODS: Genome-wide variant data from 902 Korean patients with CD and 72 179 controls were used to assess the genetic associations in a meta-analysis...

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PMID: 37523193
DOI: 10.1093/ecco-jcc/jjad127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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