Article
Fucose Binding Cancels out Mechanical Differences between Distinct Human Noroviruses.
Viruses - 30 Jun 2023
Feng Yuzhen, Pogan Ronja, Thiede Lars, Müller-Guhl Jürgen, Uetrecht Charlotte, Roos Wouter H
Abstract excerpt
The majority of nonbacterial gastroenteritis in humans and livestock is caused by noroviruses. Like most RNA viruses, frequent mutations result in various norovirus variants. The strain-dependent binding profiles of noroviruses to fucose are supposed to facilitate norovirus infection. It remains unclear, however, what the molecular mechanism behind strain-dependent functioning is. In this study, by applying...
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