Article

Fucoidan from Fucus vesiculosus can inhibit human norovirus replication by enhancing the host innate immune response

2022-06-18

Abstract excerpt

Fucoidan extracted from Fucus vesiculosus was able to inhibit the replication of human noroviruses (hNoV) GII.4[P16] in zebrafish (Danio rerio) larvae. In the hNoV infected zebrafish larvae, a transcriptomic analysis showed significant upregulation (p < 0.01) of the interferons (IFNs) signaling related genes as well as a series of IFN-stimulated genes (ISGs) encoding antiviral effectors compared to the mock-infect...

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Literature Corpus work: 3713a5d8-9694-5c61-b210-39422d6b5d25
DOI: 10.1016/j.jff.2022.105149

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