Article
Brain Tumors: Development, Drug Resistance, and Sensitization – An Epigenetic Approach
27 Jul 2023
Abstract excerpt
In this article, we describe contrasting developmental aspects of paediatric and adult brain tumours. We hypothesize that the formation of cancer progenitor cells, for both paediatric and adult, could be due to epigenetic events. However, the progression of adult brain tumours selectively involves more mutations compared to paediatric tumours. We further discuss epigenetic switches, comprising both histone...
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