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Drivers Underlying Metastasis and Relapse in Medulloblastoma and Targeting Strategies

30 Apr 2024

Abstract excerpt

Medulloblastomas comprise a molecularly diverse set of malignant pediatric brain tumors in which patients are stratified according to different prognostic risk groups that span from very good to very poor. Metastasis at diagnosis is most often a marker of poor prognosis and the relapse incidence is higher in these children. Medulloblastoma relapse is almost always fatal and recurring cells have, apart from...

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PMID: 38730706
DOI: 10.3390/cancers16091752

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