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Molecular-Targeted Therapy for Childhood Brain Tumors: A Moving Target

18 Jun 2020

Abstract excerpt

Molecular-targeted therapy is an attractive therapeutic approach for childhood brain tumors. Unfortunately, with some notable exceptions, such treatment has not yet made a major impact on survival or for that matter quality-of-life for children with brain tumors. Limitations include the specificity of any single agent to inhibit the target, the presence of multiple genetic abnormalities within a tumor, the likely...

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PMID: 32552173
DOI: 10.1177/0883073820931635

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