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Overcoming Treatment Resistance in Medulloblastoma: Underlying Mechanisms and Potential Strategies

18 Jun 2024

Abstract excerpt

Medulloblastoma is the most frequently encountered malignant brain tumor in the pediatric population. The standard of care currently consists of surgical resection, craniospinal irradiation, and multi-agent chemotherapy. However, despite this combination of multiple aggressive modalities, recurrence of the disease remains a substantial concern, and treatment resistance is a rising issue. The development of this...

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PMID: 38927954
DOI: 10.3390/cancers16122249

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