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Article

Integrated genetic analyses of immunodeficiency-associated Epstein-Barr virus- (EBV) positive primary CNS lymphomas.

Acta neuropathologica - 1 Sept 2023

Kaulen Leon D, Denisova Evgeniya, Hinz Felix, Hai Ling, Friedel Dennis, Henegariu Octavian, Hoffmann Dirk C, Ito Jakob, Kourtesakis Alexandros, Lehnert Pascal, Doubrovinskaia Sofia, Karschnia Philipp, von Baumgarten Louisa, Kessler Tobias, Baehring Joachim M, Brors Benedikt, Sahm Felix, Wick Wolfgang

Abstract excerpt

Immunodeficiency-associated primary CNS lymphoma (PCNSL) represents a distinct clinicopathological entity, which is typically Epstein-Barr virus-positive (EBV+) and carries an inferior prognosis. Genetic alterations that characterize EBV-related CNS lymphomagenesis remain unclear precluding molecular classification and targeted therapies. In this study, a comprehensive genetic analysis of 22 EBV+ PCNSL,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37495858
DOI: 10.1007/s00401-023-02613-w
PMCID: PMC10412493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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