Genomic insights into the pathogenesis of Epstein-Barr virus-associated diffuse large B-cell lymphoma by whole-genome and targeted amplicon sequencing.

doi:10.1038/s41408-021-00493-5

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Article

Genomic insights into the pathogenesis of Epstein-Barr virus-associated diffuse large B-cell lymphoma by whole-genome and targeted amplicon sequencing.

Blood cancer journal - 26 May 2021

Gebauer Niklas, Künstner Axel, Ketzer Julius, Witte Hanno M, Rausch Tobias, Benes Vladimir, Zimmermann Jürgen, Gebauer Judith, Merz Hartmut, Bernard Veronica, Harder Lana, Ratjen Katharina, Gesk Stefan, Peter Wolfgang, Busch Yannik, Trojok Peter, von Bubnoff Nikolas, Biersack Harald, Busch Hauke, Feller Alfred C

Abstract excerpt

Epstein-Barr virus (EBV)-associated diffuse large B-cell lymphoma not otherwise specified (DLBCL NOS) constitute a distinct clinicopathological entity in the current World Health Organization (WHO) classification. However, its genomic features remain sparsely characterized. Here, we combine whole-genome sequencing (WGS), targeted amplicon sequencing (tNGS), and fluorescence in situ hybridization (FISH) from 47...

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PMID: 34039950
DOI: 10.1038/s41408-021-00493-5
PMCID: PMC8155002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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