Article
Maximum mutational robustness in genotype-phenotype maps follows a self-similar blancmange-like curve.
Journal of the Royal Society, Interface - 1 Jul 2023
Mohanty Vaibhav, Greenbury Sam F, Sarkany Tasmin, Narayanan Shyam, Dingle Kamaludin, Ahnert Sebastian E, Louis Ard A
Abstract excerpt
Phenotype robustness, defined as the average mutational robustness of all the genotypes that map to a given phenotype, plays a key role in facilitating neutral exploration of novel phenotypic variation by an evolving population. By applying results from coding theory, we prove that the maximum phenotype robustness occurs when genotypes are organized as bricklayer's graphs, so-called because they resemble the way...
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