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Article

The organization of biological sequences into constrained and unconstrained parts determines fundamental properties of genotype-phenotype maps.

Journal of the Royal Society, Interface - 6 Dec 2015

Greenbury S F, Ahnert S E

Abstract excerpt

Biological information is stored in DNA, RNA and protein sequences, which can be understood as genotypes that are translated into phenotypes. The properties of genotype-phenotype (GP) maps have been studied in great detail for RNA secondary structure. These include a highly biased distribution of genotypes per phenotype, negative correlation of genotypic robustness and evolvability, positive correlation of...

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Identifiers

PMID: 26609063
DOI: 10.1098/rsif.2015.0724
PMCID: PMC4707848

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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