Predicting the topography of fitness landscapes from the structure of genotype-phenotype maps.

Abstract excerpt

Ruggedness-the prevalence of fitness peaks-and navigability-the existence of fitness-increasing paths to a target-are key factors affecting evolution on fitness landscapes. Here, we analyze these properties in landscapes that inherit biophysically grounded genotype-phenotype (GP) maps. By assuming a random phenotype-fitness assignment as a baseline, the structure of the GP maps is included without imposing...

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