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Article

Alternative splicing in prostate cancer progression and therapeutic resistance

24 Apr 2024

Abstract excerpt

Prostate cancer (CaP) remains the second leading cause of cancer deaths in western men. CaP mortality results from diverse molecular mechanisms that mediate resistance to the standard of care treatments for metastatic disease. Recently, alternative splicing has been recognized as a hallmark of CaP aggressiveness. Alternative splicing events cause treatment resistance and aggressive CaP behavior and are...

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PMID: 38658776
DOI: 10.1038/s41388-024-03036-x

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