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Integrating single-cell and bulk RNA sequencing to predict prognosis and immunotherapy response in prostate cancer

20 Sept 2023

Abstract excerpt

Prostate cancer (PCa) stands as a prominent contributor to morbidity and mortality among males on a global scale. Cancer-associated fibroblasts (CAFs) are considered to be closely connected to tumour growth, invasion, and metastasis. We explored the role and characteristics of CAFs in PCa through bioinformatics analysis and built a CAFs-based risk model to predict prognostic treatment and treatment response in...

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PMID: 37730847
DOI: 10.1038/s41598-023-42858-9

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