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Article

Phenotypic Profiling of Human Stem Cell-Derived Midbrain Dopaminergic Neurons.

Journal of visualized experiments : JoVE - 7 Jul 2023

Weiss Amélie, Sommer Peter, Wilbertz Johannes H

Abstract excerpt

Parkinson's disease (PD) is linked to a range of cell biological processes that cause midbrain dopaminergic (mDA) neuron loss. Many current in vitro PD cellular models lack complexity and do not take multiple phenotypes into account. Phenotypic profiling in human induced pluripotent stem cell (iPSC)-derived mDA neurons can address these shortcomings by simultaneously measuring a range of neuronal phenotypes in a...

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PMID: 37486112
DOI: 10.3791/65570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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