Article
Large-Scale Screening for Candidate Genes of Ossification of the Posterior Longitudinal Ligament of the Spine
1 Jan 2002
Abstract excerpt
Ossification of the posterior longitudinal ligament of the spine (OPLL) is the predominant myelopathy among Japanese, and is usually diagnosed by ectopic bone formation in the paravertebral ligament in Japanese and other Asians. To detect genetic determinants associated with OPLL, we performed an extensive nonparametric linkage study with 126 affected sib-pairs using markers for various candidate genes by...
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