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Article

Biglycan and reduced glycolysis are associated with breast cancer cell dormancy in the brain

29 Jun 2023

Abstract excerpt

Exit of quiescent disseminated cancer cells from dormancy is thought to be responsible for metastatic relapse and a better understanding of dormancy could pave the way for novel therapeutic approaches. We used an in vivo model of triple negative breast cancer brain metastasis to identify differences in transcriptional profiles between dormant and proliferating cancer cells in the brain. BGN gene, encoding a small...

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PMID: 37456245
DOI: 10.3389/fonc.2023.1191980

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