Structure of Clostridium difficile PilJ Exhibits Unprecedented Divergence from Known Type IV Pilins

Abstract excerpt

Type IV pili are produced by many pathogenic Gram-negative bacteria and are important for processes as diverse as twitching motility, cellular adhesion, and colonization. Recently, there has been an increased appreciation of the ability of Gram-positive species, including Clostridium difficile, to produce Type IV pili. Here we report the first three-dimensional structure of a Gram-positive Type IV pilin, PilJ,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antibiotic Resistance in Bacteria
• Share to Antimicrobial Resistance in Staphylococcus
• Share to Clostridium difficile and Clostridium perfringens research