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Article

Effect of MAPK activation via mutations in NRAS, KRAS and BRAF on clinical outcome in newly diagnosed multiple myeloma.

Hematological oncology - 1 Dec 2023

Perroud Camille, Thurian Dario, Andres Martin, Künzi Arnaud, Wiedemann Gertrud, Zeerleder Sacha, Bacher Ulrike, Pabst Thomas, Banz Yara, Porret Naomi, Rebmann Ekaterina

Abstract excerpt

Until now, next generation sequencing (NGS) data has not been incorporated into any prognostic stratification of multiple myeloma (MM) and no therapeutic considerations are based upon it. In this work, we correlated NGS data with (1) therapy response and survival parameters in newly diagnosed mul...

Topics

Humans
Multiple Myeloma
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins p21(ras)
Bortezomib
Lenalidomide
Mutation
Membrane Proteins
GTP Phosphohydrolases

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37452600
DOI: 10.1002/hon.3208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-37452600-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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