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Advances in the molecular characterization of multiple myeloma and mechanism of therapeutic resistance

27 Oct 2022

Abstract excerpt

Recent insight in the genomic landscape of newly diagnosed multiple myeloma (NDMM) and its precursor conditions, monoclonal gammopathy of uncertain significance (MGUS), and smoldering myeloma have allowed the identification of patients with precursor conditions with a high risk of progression. These cases with “progressor” MGUS/SMM have a higher average mutation burden, have higher rates of mutations in specific...

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PMID: 36387095
DOI: 10.3389/fonc.2022.1020011

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