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Article

Isolation of Adult Mouse Cardiac Fibroblasts

1 Jul 2023

Abstract excerpt

Fibroblasts are dynamic cells of mesenchymal origin that regulate tissue homeostasis, extracellular matrix production, and acute wound healing. Fibroblasts respond to tissue injury and inflammation by differentiating into myofibroblasts and secreting extracellular matrix proteins. Fibroblasts are the principal mediators of the fibrotic response in all tissues and organs. Adult primary fibroblasts represent an...

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PMID: 37439518
DOI: 10.1002/cpz1.840

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