Article

Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells

2023-10-22

Abstract excerpt

Abstract (Summary) Cardiac fibroblasts play an essential role in the development of the heart and have been implicated in disease progression in the context of fibrosis and regeneration. Here, we established a simple organoid culture platform using human pluripotent stem cell-derived epicardial cells and ventricular cardiomyocytes to study cardiac fibroblasts’ development, maturation and heterogeneity under normal...

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Literature Corpus work: 19395cd7-34a5-5539-a857-594c24b80c81
DOI: 10.1101/2023.10.22.563460

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