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Article

Developing a Base Editing System for Marine Roseobacter Clade Bacteria.

ACS synthetic biology - 21 Jul 2023

Wei Ying, Feng Li-Juan, Yuan Xian-Zheng, Wang Shu-Guang, Xia Peng-Fei

Abstract excerpt

The Roseobacter clade bacteria are of great significance in marine ecology and biogeochemical cycles, and they are potential microbial chassis for marine synthetic biology due to their versatile metabolic capabilities. Here, we adapted a CRISPR-Cas-based system, base editing, with the combination of nuclease-deactivated Cas9 and deaminase for Roseobacter clade bacteria. Taking the model roseobacter Roseovarius...

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PMID: 37436915
DOI: 10.1021/acssynbio.3c00259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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