Article
Prognostic value of the mutation types and dynamics of FLT3-ITD in acute myeloid leukemia.
European journal of haematology - 1 Oct 2023
Koo Mosae, Song Ik-Chan, Kim Jimyung, Kwon Gye Cheol, Kim Seon Young
Abstract excerpt
OBJECTIVE: The prognostic value of the mutation types and dynamics of FLT3-ITD in acute myeloid leukemia (AML) and other known factors were studied. METHODS: Initial and follow-up samples from 45 AML patients with FLT3-ITD mutations were analyzed by fragment length analysis, Sanger sequencing, and next-generation sequencing. RESULTS: Some patients (13%) had multiple FLT3-ITD mutations, and many of them had acute...
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