Article
Warfarin pharmacogenetics in a black Zimbabwean cohort: an observational prospective study.
Pharmacogenomics - 1 Jul 2023
M Hidjo Marie Madeleine, Chikwambi Zedias, Ngwende Gift, Matenga Jonathan A, Masimirembwa Collen
Abstract excerpt
Aim: A prospective observational study was conducted to evaluate the feasibility of implementing clinical guidelines for warfarin dosing in black Zimbabwean patients. Methods: CYP2C9*5, CYP2C9*6, CYP2C9*8 and CYP2C9*11 and VKORC1 c. 1639 G>A variations were observed in 62 study patients. Results & Conclusion: Overall, 39/62 (62.90%) participants did not receive a warfarin starting dose as would have been...
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