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Article

PHF5A regulates the expression of the DOCK5 variant to promote HNSCC progression through p38 MAPK activation

12 Jul 2023

Abstract excerpt

BACKGROUND: Previously, we identified an oncogenic splicing variant of DOCK5 in head and neck squamous cell carcinoma (HNSCC); however, the mechanism for the generation of this specific DOCK5 variant remains unknown. This study aims to explore the potential spliceosome genes involved in the production of the DOCK5 variant and validate its role in regulating the progression of HNSCC. METHODS: The differentially...

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PMID: 37434235
DOI: 10.1186/s13062-023-00396-4

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