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Article

KDM5B overexpression predicts a poor prognosis in patients with squamous cell carcinoma of the head and neck

28 Nov 2017

Abstract excerpt

Purpose: Lysine demethylase (KDM) 5B, as a member of the histone lysine demethylase family, is overexpressed and functions abnormally in various human cancers. However, its expression in the squamous cell carcinoma of the head and neck (SCCHN) remains unclear. Methods: KDM5B expression was analyzed by immunohistochemistry and correlated with clinicopathological parameters in 103 archival SCCHN tissue samples and...

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Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
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PMID: 29290786
DOI: 10.7150/jca.22145

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