Article

ZNF671 Silencing Affects Signalling Pathways in Head and Neck Cancer via Activation of Oncogenic Non-Coding RNAs

2024-08-22

Abstract excerpt

Novel ZNF proteins such as ZNF671 that are located on chromosome 19q13 are known to be hypermethylated at a high frequency in HNSCC as well as in other epithelial solid tumors. Their function is largely unknown. Here, we show that ZNF671 is epigenetically silenced in HNSCC primary tumors compared to matched adjacent normal tissue. Moreover, low expression of ZNF671 is significantly associated with decreased surviv...

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Literature Corpus work: 59d267d0-be76-5572-ba40-c9cb2b55131c
DOI: 10.20944/preprints202408.1654.v1

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