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Critical role of MXRA7 in differentiation blockade in human acute promyelocytic leukemia cells

5 Jul 2023

Abstract excerpt

The biology of the matrix remodeling-associated 7 (MXRA7) gene has been ill defined. Bioinformatic analysis of public data sets revealed that MXRA7 messenger RNA (mRNA) was highly expressed in acute myeloid leukemia (AML), especially acute promyelocytic leukemia (APL). High expression of MXRA7 was associated with poor overall survival of patients with AML. We confirmed that MXRA7 expression was upregulated in...

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PMID: 37419299
DOI: 10.1016/j.exphem.2023.07.001

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