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Article

miRNA let-7c promotes granulocytic differentiation in acute myeloid leukemia.

Oncogene - 1 Aug 2013

Pelosi A, Careccia S, Lulli V, Romania P, Marziali G, Testa U, Lavorgna S, Lo-Coco F, Petti M C, Calabretta B, Levrero M, Piaggio G, Rizzo M G

Abstract excerpt

MicroRNAs (miRNAs), small non-coding RNAs that regulate gene expression post-transcriptionally, are involved in many complex cellular processes. Several miRNAs are differentially expressed in hematopoietic tissues and play important roles in normal differentiation, but, when aberrantly regulated,...

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Share to Cell Differentiation
Share to Gene Expression Regulation, Neoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeodomain Proteins

Share to Leukemia, Myeloid, Acute

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Source

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Identifiers

PMID: 22964640
DOI: 10.1038/onc.2012.398
PMCID: PMC7228025

Genes

PBX2
PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22964640-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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