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Article

Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids.

Cell death & disease - 7 Jul 2023

Chanda Ayan, Sarkar Anusi, Deng Lili, Bonni Azad, Bonni Shirin

Abstract excerpt

Protein post-translational modification by the small ubiquitin-like modifier (SUMO) regulates the stability, subcellular localization, and interactions of protein substrates with consequences on cellular responses including epithelial-mesenchymal transition (EMT). Transforming growth factor beta (TGFβ) is a potent inducer of EMT with implications for cancer invasion and metastasis. The transcriptional coregulator...

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Identifiers

PMID: 37414747
DOI: 10.1038/s41419-023-05921-x
PMCID: PMC10326038

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Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids.PMID 37414747Read ↗

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