Article
A new model for oncogenesis. From tumour immunology to a mathematical approach of oncogenesis.
Anticancer research - 1 Jan 2000
Den Otter W, Koten J W, Derkinderen D J
Abstract excerpt
Around 1970 it was assumed that tumour cells are due to a single specific oncogenic mutation. This implied that daily many thousands of tumour cells would arise de novo and that most of these tumour cells were killed by immune surveillance or natural resistance mechanisms. Recent findings on immu...
Topics
- Age Factors
- Cell Cycle
- Child
- DNA, Neoplasm
- DNA, Viral
- Genes, Recessive
- Hormones
- Humans
- Mutation
- Neoplasms
- Oncogenes