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Article

Function of oncogenes in cancer development: a changing paradigm.

The EMBO journal - 29 May 2013

Vicente-Dueñas Carolina, Romero-Camarero Isabel, Cobaleda Cesar, Sánchez-García Isidro

Abstract excerpt

Tumour-associated oncogenes induce unscheduled proliferation as well as genomic and chromosomal instability. According to current models, therapeutic strategies that block oncogene activity are likely to selectively target tumour cells. However, recent evidences have revealed that oncogenes are only essential for the proliferation of some specific tumour cell types, but not all. Indeed, the latest studies of the...

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Identifiers

PMID: 23632857
DOI: 10.1038/emboj.2013.97
PMCID: PMC3671260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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