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Article

E-GWAS: an ensemble-like GWAS strategy that provides effective control over false positive rates without decreasing true positives.

Genetics, selection, evolution : GSE - 5 Jul 2023

Zhou Guang-Liang, Xu Fang-Jun, Qiao Jia-Kun, Che Zhao-Xuan, Xiang Tao, Liu Xiao-Lei, Li Xin-Yun, Zhao Shu-Hong, Zhu Meng-Jin

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) are an effective way to explore genotype-phenotype associations in humans, animals, and plants. Various GWAS methods have been developed based on different genetic or statistical assumptions. However, no single method is optimal for all traits and, for many traits, the putative single nucleotide polymorphisms (SNPs) that are detected by the different methods do...

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PMID: 37407918
DOI: 10.1186/s12711-023-00820-3
PMCID: PMC10320972

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