Article
Evaluating three strategies of genome-wide association analysis for integrating data from multiple populations.
Animal genetics - 1 Apr 2024
Zhong Zhanming, Li Guangzhen, Xu Zhiting, Zeng Haonan, Teng Jinyan, Feng Xueyan, Diao Shuqi, Gao Yahui, Li Jiaqi, Zhang Zhe
Abstract excerpt
In livestock, genome-wide association studies (GWAS) are usually conducted in a single population (single-GWAS) with limited sample size and detection power. To enhance the detection power of GWAS, meta-analysis of GWAS (meta-GWAS) and mega-analysis of GWAS (mega-GWAS) have been proposed to integrate data from multiple populations at the level of summary statistics or individual data, respectively. However, there...
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