Article
Emerging small molecular inhibitors as targeted therapies for high-risk acute myeloid leukemias.
Expert review of hematology - 1 Jan 2000
Sahasrabudhe Kieran D, Albrethsen Mary, Mims Alice S
Abstract excerpt
INTRODUCTION: Acute myeloid leukemia (AML) is an aggressive disease which has traditionally been treated with intensive chemotherapy. Survival in patients with high-risk cytogenetic and molecular subsets has been poor with this approach due to suboptimal responses seen with intensive chemotherapy and due to many patients with higher risk disease being older and unable to tolerate intensive therapies. In recent...
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