Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerging therapies for acute myeloid leukemia: translating biology into the clinic.

JCI insight - 21 Sept 2017

Kavanagh Simon, Murphy Tracy, Law Arjun, Yehudai Dana, Ho Jenny M, Chan Steve, Schimmer Aaron D

Abstract excerpt

Acute myeloid leukemia (AML) is an aggressive hematological malignancy with a poor outcome; overall survival is approximately 35% at two years and some subgroups have a less than 5% two-year survival. Recently, significant improvements have been made in our understanding of AML biology and genetics. These fundamental discoveries are now being translated into new therapies for this disease. This review will...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents, Immunological
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Molecular Targeted Therapy

Share to Mutation

Share to Translational Research, Biomedical

Source

Open in PubMed Open full text

Identifiers

PMID: 28931762
DOI: 10.1172/jci.insight.95679
PMCID: PMC5621868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging therapies for acute myeloid leukemia: translating biology into the clinic.PMID 28931762Read ↗

Advances in acute myeloid leukemia.Semantic proximity Read ↗

Treatment of Acute Myeloid Leukemia in the Era of Genomics—Achievements and Persisting ChallengesSemantic proximity Read ↗

Toward Individualized Therapy in Acute Myeloid Leukemia: A Contemporary Review.Semantic proximity Read ↗

[Acute myeloid leukemia: molecular pathogenesis and new therapeutic strategies].Semantic proximity Read ↗

Acute Myeloid Leukemia: Biologic, Prognostic, and Therapeutic Insights.Semantic proximity Read ↗

Recent advances in the understanding and treatment of acute myeloid leukemiaSemantic proximity Read ↗

An Overview of Targeted Therapies in Acute Myeloid LeukemiaSemantic proximity Read ↗

Acute myeloid leukemia: advancing clinical trials and promising therapeutics.Semantic proximity Read ↗

Molecular and chromosomal alterations: new therapies for relapsed acute myeloid leukemia.Semantic proximity Read ↗

Molecular pathogenesis of acute myeloid leukemia: a diverse disease with new perspectives.Semantic proximity Read ↗

Novel therapeutic strategies for AML in 2012.Semantic proximity Read ↗

‘Acute myeloid leukemia: a comprehensive review and 2016 update’Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.