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Article

Moving toward individualized target-based therapies in acute myeloid leukemia.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Feb 2023

Bazinet A, Kantarjian H M

Abstract excerpt

Acute myeloid leukemia (AML) is a heterogeneous disease at the genetic level. The field of AML therapy is increasingly shifting away from uniform approaches based solely on intensive chemotherapy (such as '7 + 3') toward personalized therapy. The treatment of AML can now be individualized based on patient characteristics and cytogenetic/molecular disease features. In this review, we provide a comprehensive...

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PMID: 36423744
DOI: 10.1016/j.annonc.2022.11.004

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