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Targeted Therapies for the Evolving Molecular Landscape of Acute Myeloid Leukemia

16 Sept 2021

Abstract excerpt

Despite considerable growth in our understanding of the heterogeneous biology and pathogenesis of acute myeloid leukemia (AML) in recent decades, for nearly forty years, little progress was gained in the realm of novel therapeutics. Since 2017, however, nine agents have been FDA-approved for patients with AML in both the upfront and relapsed/refractory (R/R) settings. Most of these compounds function as...

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PMID: 34572873
DOI: 10.3390/cancers13184646

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