Article
Acute myeloid leukemia: advancing clinical trials and promising therapeutics.
Expert review of hematology - 1 May 2016
Daver Naval, Cortes Jorge, Kantarjian Hagop, Ravandi Farhad
Abstract excerpt
Recent progress in understanding the biology of acute myeloid leukemia (AML) and the identification of targetable driver mutations, leukemia specific antigens and signal transduction pathways has ushered in a new era of therapy. In many circumstances the response rates with such targeted or antibody-based therapies are superior to those achieved with standard therapy and with decreased toxicity. In this review we...
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